Publications
Preprints
Christian Vanhille-Campos, Kevin D. Whitley, Philipp Radler, Martin Loose, Séamus Holden, and Anđela Šarić.
Self-organisation of mortal filaments: the role of FtsZ treadmilling in bacterial division ring formation
bioRxiv 2023.05.08.539808 (Preprint)
Paulina Kettel, Laura Marosits, Elena Spinetti, Michael Rechberger, Philipp Radler, Isabell Niedermoser, Irmgard Fischer, Gijs A Versteeg, Martin Loose, Roberto Covino, G Elif Karagöz.
Stress-induced clustering of the UPR sensor IRE1 is driven by disordered regions within its ER lumenal domain
bioRxiv 2023.03.30.534746 (Preprint)
2024
Nataliia Gnyliukh , Alexander Johnson, Marie-Kristin Nagel, Aline Monzer, David Babić, Annamaria Hlavata, Saqer S. Alotaibi, Erika Isono, Martin Loose*, Jiří Friml*.
Role of dynamin-related proteins 2 and SH3P2 in clathrin-mediated endocytosis in Arabidopsis thaliana
Journal of Cell Science (2024): jcs-261720.
Phillip Nußbaum, Danguole Kureisaite-Ciziene, Dom Bellini, Chris van der Does, Marko Kojic, Najwa Taib, Simonetta Gribaldo, Martin Loose, Jan Löwe, Sonja-Verena Albers.
PRC domain-containing proteins modulate FtsZ-based archaeal cell division
Nature Microbiology (2024). https://doi.org/10.1038/s41564-024-01600-5
Feyza Nur Arslan, Edouard Hannezo, Jack Merrin, Martin Loose, Carl-Philipp Heisenberg.
Adhesion-induced cortical flows pattern E-cadherin-mediated cell contacts
Current Biology (2024), vol. 34, 1, P171-182.E8,
Philipp Radler & Martin Loose.
A dynamic duo: Understanding the roles of FtsZ and FtsA for Escherichia coli cell division through in vitro approaches
European Journal of Cell Biology (2024), vol 103, 1, 151380.
2023
Zuzana Dunajova, Batirtze Prats Mateu, Philipp Radler, Keesiang Lim, Dörte Brandis, Philipp Velicky, Johann Georg Danzl, Richard W Wong, Jens Elgeti, Edouard Hannezo, Martin Loose.
Chiral and nematic phases of flexible active filaments
Nature Physics (2023) Nat. Phys. 19, 1916–1926.
Thomas Leonhard*, Martin Loose*, Sascha Martens*
The membrane surface as a platform that organizes cellular and biochemical processes
Developmental Cell (2023), vol. 58, 15, 1315-1332. (Review)
Martin Loose, Albert Auer, Gabriel Brognara, Hanifatul Rahmah Budiman, Lukasz Kowalski, Ivana Matijević.
In vitro reconstitution of small GTPase regulation
FEBS Lett (2023), vol. 597, 762–777 (Review)
2022
Philipp Radler, Natalia Baranova, Paulo Caldas, Christoph Sommer, Mar López-Pelegrín, David Michalik, Martin Loose.
In vitro reconstitution of Escherichia coli divisome activation
Nature Communications (2022), vol. 13, 2635
2021
Alexander Johnson, Dana A Dahhan, Nataliia Gnyliukh, Walter A Kaufmann, Vanessa Zheden, Tommaso Costanzo, Pierre Mahou, Mónika Hrtyan, Jie Wang, Juan Aguilera-Servin, Daniël van Damme, Emmanuel Beaurepaire, Martin Loose, Sebastian Y Bednarek, Jiri Friml.
The TPLATE complex mediates membrane bending during plant clathrin-mediated endocytosis
PNAS (2021), 118 (51) e2113046118.
Labajová N, Baranova NS, Jurásek M, Vácha R, Loose M, Barák I.
Cardiolipin-containing lipid membranes attract the bacterial cell division protein DivIVA.
International Journal of Molecular Sciences (2021). 22(15), 8350.
Víctor M. Hernández-Rocamora, Natalia Baranova, Katharina Peters, Eefjan Breukink, Martin Loose*, Waldemar Vollmer*.
Real time monitoring of peptidoglycan synthesis by membrane-reconstituted class A penicillin binding proteins.
eLife (2021); 10:e61525
Keisuke Ishihara, Franziska Decker, Paulo Caldas, James Pelletier, Martin Loose, Jan Brugues, Timothy J. Mitchison.
Spatial Variation of Microtubule Depolymerization in Large Asters
Molecular Biology of the Cell (2021), vol. 32(9):823-1005
Christian Duellberg, Albert Auer, Nicola Canigova, Katrin Loibl, Martin Loose.
In vitro reconstitution reveals phosphoinositides as cargo-release factors and activators of the ARF6 GAP ADAP1
PNAS (2021), vol. 118 (1) e2010054118.
2020
Paulo Caldas, Philipp Radler, Christoph Sommer and Martin Loose.
Computational analysis of filament polymerization dynamics in cytoskeletal networks.
Methods in Cell Biology (2020), vol. 158:145-161.
Urban Bezeljak, Hrushikesh Loya, Beata Kaczmarek, Timothy E. Saunders and Martin Loose.
Stochastic activation and bistability in a Rab GTPase regulatory network.
PNAS (2020), vol. 117(12):6540-6549.
Natalia Baranova, Philipp Radler, Victor M. Hernandez-Rocamora, Carlos Alfonso, Mar Lopez-Pelegrin, German Rivas, Waldemar Vollmer, Martin Loose.
Diffusion and capture permits dynamic coupling between treadmilling FtsZ filaments and cell division proteins.
Nature Microbiology (2020), vol. 5(3):407-417.
2019
Paulo Caldas, Mar Lopez-Pelegrin, Daniel J.G. Pearce, Nazmi B. Budanur, Jan Brugues, Martin Loose.
Cooperative ordering of treadmilling filaments in cytoskeletal networks of FtsZ and its crosslinker ZapA.
Nature Communications (2019), vol. 10 (1), 5744.
2017
Natalia Baranova and Martin Loose.
Single molecule measurements to study polymerization dynamics of FtsZ-FtsA copolymers.
Methods in Cell Biology (2017) vol. 137:355-370.
Hansen, A. H., Duellberg, C., Mieck, C., Loose, M. & Hippenmeyer, S.
Cell Polarity in Cerebral Cortex Development—Cellular Architecture Shaped by Biochemical Networks.
Front Cell Neurosci 11, 886 (2017).
Martin Loose, Katja Zieske and Petra Schwille.
Reconstitution of protein dynamics involved in bacterial cell division.
Springer Subcellular Biochemistry: Prokaryotic Cytoskeleton (2017), vol. 84:419-444.
before 2016
Phuong A. Nguyen, Christine M. Field, Aaron C. Groen, Timothy J. Mitchison, Martin Loose.
Using supported bilayers to study the spatiotemporal organization of membrane-bound proteins.
Methods in Cell Biology (2015) vol. 128:223-41.
Phuong A. Nguyen*, Aaron C. Groen*, Martin Loose, Keisuke Ishihara, Martin Wühr, Christine M. Field, Timothy J. Mitchison.
Spatial Organization of Cytokinesis Signaling Reconstituted in a Cell-Free System.
Science (2014) vol. 346, 244-247
*equal contribution.
Martin Loose and Timothy J. Mitchison.
The bacterial cell division proteins FtsA and FtsZ self-organize into dynamic cytoskeletal patterns.
Nature Cell Biology (2014) vol. 16, 38–46.
Mike Bonny, Elisabeth Fischer-Friedrich, Martin Loose, Petra Schwille, Karsten Kruse.
Membrane Binding of MinE Allows for a Comprehensive Description of Min-Protein Pattern Formation.
PLoS Comput Biol (2013) vol.9(12): e1003347.
Jakob Schweizer+, Martin Loose+*, Mike Bonny, Ingolf Mönch, Karsten Kruse and Petra Schwille.
Geometry sensing by self-organized protein patterns.
PNAS (2012) vol. 109(38) pp. 15283-8.
*corresponding authors, +equal contribution.
Martin Loose, Karsten Kruse and Petra Schwille.
Protein self-organization: Lessons from the Min system.
Annual Reviews for Biophysics (2011) vol. 40 pp. 31536.
Martin Loose, Elisabeth Fischer-Friedrich, Christoph Herold, Karsten Kruse and Petra Schwille.
Min protein patterns emerge from rapid rebinding and direct membrane interaction of MinE.
Nature Structural & Molecular Biology (2011) vol. 18(5) pp. 577-83.
Ana Dinarina*, Céline Pugieux*, Maria Corral, Martin Loose, Joachim Spatz and François Nédélec.
Chromatin shapes the mitotic spindle.
Cell (2009) vol. 138(3) pp. 502-13.
Martin Loose and Petra Schwille.
Biomimetic membrane systems to study cellular organization.
Journal of Structural Biology (2009) vol. 168(1) pp. 143-51. (Review)
Martin Loose, Elisabeth Fischer-Friedrich, Jonas Ries, Karsten Kruse and Petra Schwille.
Spatial regulators for bacterial cell division self-organize into surface waves in vitro.
Science (2008) vol. 320 (5877) pp. 789-92